Yellow fever

Yellow fever

Yellow fever (YF) is a viral disease that is transmitted by mosquitoes, which affects humans and other primary strains. This disease is currently found in more than 43 countries in the tropical regions of Africa and the Americas. Yellow fever infection can be asymptomatic or can cause a wide range of diseases, ranging from mild symptoms to severe illness accompanied by haemorrhage and jaundice and ultimately to death. More than 30,000 deaths occur annually due to this infection, and this number will be much higher if not vaccinated. The Aedes aegypti (yellow fever mosquito) is the most important vector. Transmission is complex and has different characteristics in different endemic areas. All yellow fever vaccines currently available are live and attenuated vaccines and are based on attenuation variables 17d. WHO is currently prequalifying vaccines from four manufacturers. it vaccination is carried out for three main reasons: to protect the population living in areas prone to endemic and epidemic disease, to protect travellers visiting these areas, and to prevent the spread of the disease internationally by reducing the risk of introducing the virus through travellers who have a viral infection. A single dose of it vaccine is enough to give a lifelong protective immunity against it. Given the ongoing transmission of the yellow fever virus and the proven efficacy and security of it vaccination, WHO recommends that all countries affected by the disease should enter it vaccine into routine immunization programs. Vaccines should be offered to all unvaccinated travellers under the age of 9 months who travel to and from areas at risk, unless they belong to a group of individuals who are prohibited from taking it vaccinations. Well-designed and supported studies with sufficient energy are required to assess the simultaneous consumption of yellow fever vaccine with other live vaccines, including measles, mumps and rubella vaccines and to assess the safety and immune action of yellow fever vaccines in pregnant women and in people younger than or equal to sixty years of age.

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